From the Archives: Paul Glimcher and Decision-Making

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Paul Glimcher at Neuroscience 2013, in San Diego. Photo: Nicky Penttila

Our latest Report on Progress is a clear and accessible review of the field of neuroeconomics. “Understanding Human Decision-Making: Neuroeconomics” is by Dana Alliance member Paul Glimcher, Ph.D. Glimcher embodies the Alliance’s commitment to sharing brain science information and discoveries with all—science-curious, science-committed, and even intrigued sports fans.

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Free Public Event: The Aging Brain

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Image: Shutterstock

What does every congressional district have in common? Baby Boomers – the sizable generation of people now in their 50s to 70s. It is well documented that the collective aging of the Boomers will have public health impacts. This includes the impacts of the aging brain. Come and learn what happens to the brain as we get older, what happens when the process goes wrong, and what we can do to strengthen the brain as we age.

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Changing the World with Smartphones

“We are wildly ambitious,” Tom Insel, M.D., says when asked about his plans for Verily Life Sciences, a research organization parented by Google. After 13 years, Insel rocked the world of brain science when he announced plans to step down as director of the National Institute of Mental Health (NIMH) in late 2015. His departure from NIMH, however, wasn’t a leave from neuroscience research or public health; it was a progressive step towards advancing the technologies that are predicted to transform mental health care.

Recently, Insel was profiled in the July/August 2017 issue of The Atlantic, which offers a thorough look at the trajectory that took him from lead role at the world’s largest mental health research institution to complete submersion in the energetic tech bubble of Silicon Valley.

The article recounts Insel’s early work in behavioral research, as well as his influence on the field of antidepressants and NIMH’s involvement in clinical drug trials. Presented with an opportunity to direct a new mental health team under Google, he could now focus on taking applied research and use it to help millions of people globally, who are in need of mental health care. “At any given moment, roughly one in seven of the world’s 7.5 billion people is struggling with mental illness. ‘We’re not going to reach all those people by hiring more psychiatrists,’ says Insel. But we might reach them with smartphones.”

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Summer 2017 Brainy Reading List

Summer is finally here! We have eight brainy book suggestions, all written by members of the Dana Alliance for Brain Initiatives (DABI) or prominent neuroscientists, to take to the pool, beach, or wherever you enjoy a little bit of sun:

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New Method Reaches Deep in the Brain Without Surgery

A team of neuroscientists and engineers are working to develop a new form of treatment for people who have Parkinson’s disease, depression, or obsessive-compulsive disorder. According to a recent New York Times article, the available methods for treating these conditions currently involve the risks of surgery and can have limited ability with directing electrical pulses to the right areas of the brain.

Dana Alliance member Helen Mayberg, tells the Times:

They have this clever new way to deliver current[s] to a spot of interest deep in the brain and do it without invading the brain…If you didn’t have to actually open up somebody’s brain and put something in it, if it could do what we’re doing now just as well—sign me up.

So far the research has only been conducted in mice, but experts are hoping the technique will work for people, too. “This is something that many of us in the field have wished for for a long time,” says Alexander Rotenberg. Rotenberg is director of the neuromodulation program at Boston Children’s Hospital and Harvard Medical School. The article goes on to explain the details of the non-invasive treatment:

The method, called temporal interference, involves beaming different electric frequencies, too high for neurons to respond to, from electrodes on the skull’s surface. The team found that where the currents intersected inside the brain, the frequencies interfered with each other, essentially canceling out all but the difference between them and leaving a low-frequency current that neurons in that location responded to.

For more information on the experimental study, read the full article here.

– Seimi Rurup

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