Dana Grantee Aims to Offer a More Personalized Treatment for Depression

DrEtkin_Jan2013_8880_5x7eIn an effort to create a more personalized approach to treating depression and to better understand its underlying circuitry, Amit Etkin of Stanford University is studying the use
of repetitive transcranial magnetic stimulation (rTMS) in combination with whole-brain EEG and functional MRI. According to Etkin:

By stimulating brain activity and assessing circuit-level changes as they happen, we can garner important insight into what is wrong in depression and how to fix it in an optimized, personalized matter.

I’ll give you one concrete example: It matters whether stimulation is done to an area in the patient’s brain that is abnormal or normal. For any treatment in any psychiatric disorder, we don’t actually know whether the goal of treatment is to normalize abnormal brain activity or to engage compensatory circuitry. It’s a fundamental question that we cannot answer without a direct tool for manipulating brain systems and assessing the effects.

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Former Dana Grantee’s Newly Published Study Hailed as the ‘Future of Bioelectronic Medicine’

Tracey_KevinThe Wall Street Journal recently highlighted former Dana grantee Kevin Tracey’s latest research.  The July 8th article, “The Future of Bioelectronic Medicine,” detailed Tracey’s newly published study, which is the first in-human investigation of implanted electronic devices as a treatment for rheumatoid arthritis.  Rheumatoid arthritis (RA) is a disorder that occurs when the body’s immune system mistakenly attacks healthy tissue, causing chronic swelling, inflammation, and joint pain.  The drugs currently used to manage the disease are not always effective, leaving many patients looking for other treatment options.  Continue reading

A Study of Motivation

Adcock, R. Alison_heashot“What makes us curious? What makes us play with our environment and investigate it? Why are some people more curious than others—and why does my own curiosity wax and wane over time?” These are questions Dana Foundation grantee R. Alison Adcock has asked herself since she was child, and which have led her to focus her scientific research on motivation.

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Former Dana grantee Beth Stevens joins ranks of MacArthur ‘geniuses’

Stevens_Beth

Early last week, the MacArthur Foundation announced the 2015 MacArthur Fellows. Former Dana grantee Beth Stevens was among the 24 recipients. According to MacArthur President Julia Stasch, the award goes to individuals who are “shedding light and making progress on critical issues, pushing the boundaries of their fields, and improving our world in imaginative, unexpected ways.” The fellowship, colloquially known as the MacArthur ‘genius grant,’ comes with a $625,000 ‘no-strings-attached’ stipend to allow recipients to “advance their expertise [and] engage in bold new work.”

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Scientists Weigh in on Special Needs Learning

“Allowing children to fail, to think they’re ‘dumb,’ is no longer acceptable,” said Dana Alliance member Sally Shaywitz at a recent Capitol Hill briefing on what neuroscience can tell us about educating special needs children.


Shaywitz, co-director of the Yale Center for Dyslexia and Creativity, joined fellow panelists Dana Alliance member Martha Denckla and Damien Fair for a discussion that addressed the importance and the difficulty of early detection of learning disorders such as dyslexia and attention deficit hyperactivity disorder (ADHD). As reported by the American Association for the Advancement of Science (AAAS):

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