Aphasia Awareness Month Interview with Kenneth Heilman, M.D.

For a devastating language disorder that affects almost two million people in the US alone, about 85 percent of people in a national survey have never heard the term “aphasia.” More common than Parkinson’s disease, cerebral palsy, or muscular dystrophy, it does not discriminate according to age, race, or gender. With June being Aphasia Awareness Month, we asked Kenneth M. Heilman, M.D., to help us get the word out.

Heilman, who is an expert in language and speech disorders, was Chief of Medicine at NATO Hospital in Turkey during the Vietnam War and currently is a Distinguished Professor Emeritus of Neurology at the University of Florida (UF) and a staff neurologist at the Malcom Randall Veterans Affairs Medical Center. Heilman has also been a member of the Dana Alliance for Brain Initiatives since 2003.

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Photo courtesy of Kenneth Heilman

Aphasia is more common than other well-known brain disorders, with an estimated 180,000 people predicted to develop it each year. Why do people know so little about it? Continue reading

#WSF18: Our Microbiome and the Brain

On Saturday at the World Science Festival, microbiologists David Relman, Jo Handelsman, Rob Knight, and Martin Blaser convened for a discussion on how the microbiome relates to our health. Our microbiome, the collective bacteria, viruses, fungi and other microorganisms that live in the digestive tract, allows us to digest food properly and fight off disease. Research suggests that an unhappy microbiome may contribute to autoimmune diseases, allergies, depression, and even Alzheimer’s.

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From left: Moderator Emily Senay; David Relman, M.D.; Rob Knight; Jo Handelsman; and Martin Blaser, M.D. Photo: World Science Festival/Greg Kessler

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National Parkinson’s Awareness Month Interview with Robert Edwards, M.D.

Parkinson’s disease (PD) is a chronic, degenerative neurological disorder that affects roughly one in 100 people over the age of 60. With no biomarker or objective test to make a definitive diagnosis, PD has kept researchers searching for clues on how to treat, and hopefully prevent, the disease.

April is National Parkinson’s Disease Awareness Month, and so we sat down with Dana Alliance for Brain Initiatives member Robert Edwards, M.D., who specializes in the treatment of PD at the Parkinson’s Disease and Movement Disorders Clinic. Edwards is a professor of neurology and physiology at the University of California, San Francisco. His lab has received international recognition for demonstrating that vesicular monoamine transport protects against MPTP toxicity, suggesting an important mechanism that may also protect against Parkinson’s.

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Robert Edwards, M.D.

Regular exercise is proven to have positive effects on gait speed, strength, balance, and overall quality of life for people with PD. Though studies are still limited, dance therapy is said to greatly improve quality of life for this group, even more so than typical exercise. Can you talk a little bit about this?

RE: I am not an expert in this area, but exercise has clear short-term effects on function and for those more severely affected, on quality of life—those earlier in the disease are doing pretty well in any case. Presumably, exercise helps by improving the function of the basal ganglia circuitry that controls movement, much as it would in normal individuals. Dance therapy focuses on balance and other aspects of motor function different from standard exercises, so might be expected to add something new. Continue reading

Successful Aging & Your Brain at Marlene Meyerson JCC Manhattan

After an inaugural, successful, and sold-out program last September, Marlene Meyerson JCC Manhattan partnered with the Dana Foundation once again to present Successful Aging & Your Brain (SA&YB) Tuesday evening—this time in celebration of Brain Awareness Week!

Speaker Matthew Fink, M.D., Neurologist-in-Chief at New York-Presbysterian and chairman, neurology at Weill Cornell Medicine, has participated as a panelist for SA&YB programs multiple times and has also frequently spoken at Marlene Meyerson JCC Manhattan. He discussed brain function, changes in the brain as we age, memory, brain diseases and disorders, and maximizing brain function and health.

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Unlocking the Diseases of the Brain

Guest blog by Carl Sherman

One evening last week, I met the mini-brain.

I was introduced to this intriguing concept by three scientists who know it intimately, at a presentation on “Unlocking Diseases of the Brain with Stem Cells,” at the headquarters of the New York Stem Cell Foundation (NYSCF).

Melissa J. Nirenberg, M.D., Ph.D., NYSCF’s chief medical officer, introduced the subject from the perspective of a neurologist with 20 years’ experience, primarily with patients with Parkinson’s disease and other movement disorders.

“It was frustrating,” she said. While treatment can attenuate some symptoms for some patients, “we don’t have anything to offer them to halt or even slow disease progression.” The same goes for Alzheimer’s. “That’s why I’m here. At NYSCF, we’re focusing on treating the underlying disorders.”

Science Laboratory

Image: Shutterstock

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