While considering whether to go to medical school, Dana Alliance member Reisa Sperling, M.D., noticed her grandfather had started to act strangely. She only later realized that he had symptoms of Alzheimer’s disease. His death when she was a neurology resident, along with her father’s diagnosis, influenced her decision to focus her research on the early detection of Alzheimer’s. She is now the director of clinical research at the Center for Alzheimer’s Research and Treatment at Brigham and Women’s Hospital in Boston. Sperling discussed her personal experience with the disease, and her ongoing research, in a fall interview for the Harvard Medical Labcast.