The Neuroscientist Who Lost Her Mind

barbara lipska

Photo courtesy of the Rubin Museum

On a recent night at New York’s Rubin Museum of Art, neuroscientist Barbara Lipska, Ph.D., sat down with journalist Jake Halpern as part of the museum’s annual Brainwave series. The discussion gave audience members the unique opportunity to hear a lucid perspective of what it’s like to experience psychosis. The interview was also particularly intimate because, in addition to his successful career as a writer, Halpern also happens to be Lipska’s son-in-law. His questions stemmed from firsthand experiences he shared with her as she battled malignant brain tumors that caused the psychotic episodes and nearly took her life.

As director of the Human Brain Collection Core at the National Institute of Mental Health, Lipska studies schizophrenia by analyzing postmortem brain dissections and observing the behavior of rats that have a disconnection between the hippocampus and prefrontal cortex. “They’re actually not as different as we would like to think,” she said of the rats. “They’re smaller, that’s for sure, and they don’t have this convoluted frontal cortex. But they are very intelligent animals, and they know what they have to do to get a reward.”

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