Sleep Disorders as Prologue to Disease: From the Archives

What a (incremental) difference seven years make. In 2009, when we wrote about Dana Alliance member David Holtzman’s work, the headline was “Could Sleep Disorders Contribute to Alzheimer’s?” This month, Scientific American describes the work he and colleagues at Washington University School of Medicine in St. Louis are doing using the headline “Why Sleep Disorders May Precede Parkinson’s and Alzheimer’s.” We’ve gone from “maybe take a look” to “what’s the mechanism” on evidence for a link between sleep troubles and risk for neurodegenerative disorders has come.

Scientific American’s Simon Makin calls the Holtzman lab’s 2009 discovery the “best evidence for a causal relationship” From our story:

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