Unlocking the Diseases of the Brain

Guest blog by Carl Sherman

One evening last week, I met the mini-brain.

I was introduced to this intriguing concept by three scientists who know it intimately, at a presentation on “Unlocking Diseases of the Brain with Stem Cells,” at the headquarters of the New York Stem Cell Foundation (NYSCF).

Melissa J. Nirenberg, M.D., Ph.D., NYSCF’s chief medical officer, introduced the subject from the perspective of a neurologist with 20 years’ experience, primarily with patients with Parkinson’s disease and other movement disorders.

“It was frustrating,” she said. While treatment can attenuate some symptoms for some patients, “we don’t have anything to offer them to halt or even slow disease progression.” The same goes for Alzheimer’s. “That’s why I’m here. At NYSCF, we’re focusing on treating the underlying disorders.”

Science Laboratory

Image: Shutterstock

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Sondheim and Pinker on Music and Emotion

When it comes to explanations for human behavior, preeminent experimental psychologist Steven Pinker, Ph.D., adamantly believes that genes matter. When others question this position, claiming that attributing emotion and behavior to genetics is merely a way of evading responsibility, Pinker will often offer a cultural rather than a scientific response:

Dear kindly Sergeant Krupke,

You gotta understand

It’s just our bringing up-ke,

That gets us out of hand.

Our mothers are all junkies,

Our fathers all are drunks.

Golly Moses naturally we’re punks

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