From the Archives: Imaging Depression

This month, Helen Mayberg and her colleagues published a study suggesting that patterns of brain connectivity may predict which people with depression would respond best to talk therapy and which would do better with a drug. This video clip from Fox5 Atlanta describes the study, and shows what it could mean to people who need help for their depression.

Our first work with Mayberg, now a member of the Dana Alliance for Brain Initiatives, was more than a decade ago, when she was using first positron emission tomography and then deep brain stimulation for treatment-resistant depression (Dana grants in 2006, 2010). She spoke with us about this work in 2012:

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Dana News E-Blast: February

Here are some stories recently posted on dana.org

Cerebrum-February 2016-Lithium-Article ContentLithium to the Rescue

by Richard S. Jope, Ph.D., and Charles B. Nemeroff, M.D., Ph.D.

New research reveals lithium’s role as a neuroprotector and suggests that enzymes modulated by lithium could lead to new treatments for Alzheimer’s, Parkinson’s, multiple sclerosis, and other neurodegenerative disorders. From Cerebrum, our online magazine of ideas.

New Clues to the Causes of Bipolar Disorder

Cell and animal models point to abnormalities in two brain areas. Continue reading

Dana News E-Blast: August

Here are some stories recently posted on www.dana.org:

The Holy Grail of Psychiatry

Photo credit: Shutterstock

by Charles B. Nemeroff, MD, PhD

In 2013, a group led by Helen Mayberg published a groundbreaking paper that sought an answer to one of the most discussed conundrums in psychiatry: Can specific patterns of brain activity indicate how a depressed person will respond to treatment? Our author examines the findings and their potential impact on treatment for a public health problem that affects millions of people worldwide. From Cerebrum, our online magazine of ideas.

Study of Alpha Synuclein ‘Strains’ Deepens Understanding of Parkinson’s and Related Diseases

Findings also hint that “synucleinopathies” may in rare cases be contagious.

ALS: A Mystery Almost Solved?

Scientists seem to be zeroing in on the once-elusive mechanisms of ALS, and are starting to design and test therapies that target those mechanisms. One of our series of Briefing Papers.

Clue to Brain Regeneration Discovered in Certain Lab Mice

Finding hints at future treatment strategy for traumatic brain injury, stroke, and Alzheimer’s.

Axons Help New Neurons Travel During Development

Recent research provides strong evidence that pollutants cause harms, and suggests underlying pathways and mechanisms.

stayingsharpbookStaying Sharp: Successful Aging and the Brain

When is memory loss a sign of dementia? What actions can be taken to help maintain brain health? Our new, free booklet gives answers to these and other memory-oriented questions in easy-to-understand language. (link is direct to PDF)

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