From the Archives: Rita Levi-Montalcini

Levi-Montalcini_featDana Alliance member Piergiorgio Strata has just published “Rita Levi-Montalcini and her major contribution to neurobiology” in Rendiconti Lincei; its English version is open-access for reading via Springer Publishing. Its 17 pages are filled with family and science-family photos, including as she entered medical school and when she was awarded a Nobel Prize, and her major scientific collaborators, as well as classic illustrations of her work in neuroembryology and much more (she lived to age 103). Her personal story is inspiring—including doing seminal research at home during wartime in Italy after she was banned from entering formal research facilities because of her faith.

“Life does not end with death. What you pass on to others remains. Immortality is not the body, which will one day die. That does not matter… of importance is the message you leave to others,” said Levi-Montalcini, who was also a founding European Dana Alliance for the Brain member. We were working with her to publish a translation of her latest memoir into English when she died, in 2012. Continue reading

Neuroscience and Society: Autism

When we’re trying to help people who have troubles due to autism spectrum disorders, one of the first challenges is definition: What does “autism” mean?

“Autism was and is still currently defined by behaviors,” Dana Alliance member Barry Gordon said, as researchers haven’t yet found solid biomarkers or other internal signals to identify it. “Whenever you read about autism, you might want to dig into what definitions they go into,” he said during a recent discussion at the American Academy for the Advancement of Sciences (AAAS) in Washington, DC.

Autism -Dawson - Oct2018Even definitions by behavior vary. For example, fellow presenter Daniel Geschwind said, problems with language used to be part of the diagnosis, but now doctors and other caregivers usually only count differences in social behavior and the presence of “repetitive-restrictive” behavior (like hand-flapping or always needing to do activities in the same order).

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Free Public Event on Autism

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Autism is a mysterious and puzzling disorder. In 1943, American child psychiatrist Leo Kanner first published a paper describing 11 children who were highly intelligent but displayed “a powerful desire for aloneness” and “an obsessive insistence on persistent sameness.” He called this condition “early infantile autism.” Prior to that time, people with autism were simply called insane. Autism is now officially known as autism spectrum disorder (ASD) and, while there is a wide variation in the nature and severity of its signs, people with ASD typically have difficulty with social communication and interaction, restricted interests, and repetitive behaviors. Continue reading

Eric Kandel is Alan Alda’s Podcast Guest

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Image courtesy of Alda Communication Training Co.

On the latest episode of the Clear + Vivid podcast, host Alan Alda, well-known actor, writer, and, in recent years, crusader of science outreach, sits down with old friend and Dana Alliance for Brain Initiatives member Eric R. Kandel, director of the Kavli Institute for Brain Science at Columbia University and author of The Disordered Mind: What Unusual Brains Tell Us About Ourselves. Kandel speaks to Alda about his work, the satisfaction of connecting with audiences, and fleeing Austria in the aftermath of its annexation to Nazi Germany.

The podcast focuses on communication and connection. It’s through conversations with individuals holding mastery in various fields that Alda guides the listener, stopping to appreciate peaks and valleys of the art form. In this, Alda and Nobel Laureate Kandel find and sustain a relaxed stride, offering listeners morsels of wisdom: The importance of being mindful of your audience, focusing on one person and changing your approach based on their responses (favorable or not); the role of laughter in forming connections; and the delicate dance of simplifying your ideas to a lay audience without treading on and distorting the science. Continue reading

In Memoriam: Nobel Laureate Arvid Carlsson, a Pioneer in Parkinson’s Treatment

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Photo: Johan Wingborg/University of Gothenburg

We regret to announce the loss of Dana Alliance member Arvid Carlsson, M.D., Ph.D., who passed away last Friday at 95 years old. Carlsson laid the groundwork for the treatment of Parkinson’s disease by discovering dopamine is a neurotransmitter that plays an important role in motor function. In 2000, this research won him the Nobel Prize in Physiology or Medicine with fellow Dana Alliance members Eric R. Kandel, M.D., and Paul Greengard, Ph.D., “for their discoveries concerning signal transduction in the nervous system.”

In 2001, Dana Alliance member John H. Byrne, Ph.D., wrote a Dana Foundation Cerebrum article to commemorate the 2000 Nobel Prize in Physiology or Medicine. He detailed Carlsson’s journey to his Nobel Prize winning research on dopamine:

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