Sleep Disorders as Prologue to Disease: From the Archives

What a (incremental) difference seven years make. In 2009, when we wrote about Dana Alliance member David Holtzman’s work, the headline was “Could Sleep Disorders Contribute to Alzheimer’s?” This month, Scientific American describes the work he and colleagues at Washington University School of Medicine in St. Louis are doing using the headline “Why Sleep Disorders May Precede Parkinson’s and Alzheimer’s.” We’ve gone from “maybe take a look” to “what’s the mechanism” on evidence for a link between sleep troubles and risk for neurodegenerative disorders has come.

Scientific American’s Simon Makin calls the Holtzman lab’s 2009 discovery the “best evidence for a causal relationship” From our story:

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Summer Reading List: Brain Books

Last year I wrote a summer reading list blog, highlighting brain books recently published by members of the Dana Alliance for Brain Initiatives. Since then, our members have published a number of new books on topics ranging from addiction to free will to neurogastronomy. When you get around to finishing the Fifty Shades of Grey trilogy (it’s everywhere!), here are some great books to keep in mind (descriptions are taken directly from the publishers’ websites).

The Addicted Brain: Why We Abuse Drugs, Alcohol, and Nicotine, by Michael Kuhar, FT Science Press.
“Addiction destroys lives. In The Addicted Brain, a leading neuroscientist explains how and why this happens–and presents advances in treatment and prevention. Using breathtaking brain imagery and other research, Michael Kuhar, Ph.D., shows the powerful, long-term brain changes that drugs can cause, revealing why it can be so difficult for addicts to escape their grip.”

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