National Parkinson’s Awareness Month Interview with Robert Edwards, M.D.

Parkinson’s disease (PD) is a chronic, degenerative neurological disorder that affects roughly one in 100 people over the age of 60. With no biomarker or objective test to make a definitive diagnosis, PD has kept researchers searching for clues on how to treat, and hopefully prevent, the disease.

April is National Parkinson’s Disease Awareness Month, and so we sat down with Dana Alliance for Brain Initiatives member Robert Edwards, M.D., who specializes in the treatment of PD at the Parkinson’s Disease and Movement Disorders Clinic. Edwards is a professor of neurology and physiology at the University of California, San Francisco. His lab has received international recognition for demonstrating that vesicular monoamine transport protects against MPTP toxicity, suggesting an important mechanism that may also protect against Parkinson’s.

robertedwards

Robert Edwards, M.D.

Regular exercise is proven to have positive effects on gait speed, strength, balance, and overall quality of life for people with PD. Though studies are still limited, dance therapy is said to greatly improve quality of life for this group, even more so than typical exercise. Can you talk a little bit about this?

RE: I am not an expert in this area, but exercise has clear short-term effects on function and for those more severely affected, on quality of life—those earlier in the disease are doing pretty well in any case. Presumably, exercise helps by improving the function of the basal ganglia circuitry that controls movement, much as it would in normal individuals. Dance therapy focuses on balance and other aspects of motor function different from standard exercises, so might be expected to add something new. Continue reading

Don’t Write Wrong

What’s the best argument for scientists responsibly communicating their findings to patients?

“We are all patients, sooner or later,” said doctor and researcher Edward Wild. And we will all want to know the latest on whatever disease we have.

For example, Wild said, when he meets with his patients who have Huntington’s disease, first they talk about their illness, and then they want to know about the latest research–and why no one tells them about it. Their family members, worried that they, too, may develop Huntington’s, read “overblown ‘cure’ research in news stories” and panic.

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