Predicting Suicides—Beyond STARRS

News Story from dana.org

Suicide Prevention

Image: Shutterstock

Over the past few years, America has lost several celebrities, including actor/comedian Robin Williams and fashion designer Kate Spade, to suicide. It’s not a surprise: Suicide rates have been increasing across the board in the United States. According to the National Institute of Mental Health (NIMH), 1.3 million people in the US attempted suicide in 2016 – and nearly 45,000 died. This is nearly a 25 percent increase from the numbers posted in 2000.

To help combat what is being called a problem of epidemic proportions, the Mental Health Research Network, led by researchers at Kaiser Permanente, has developed a computer model based on data collected during outpatient visits to help identify which patients may be at the most risk for killing themselves.

Continue reading

The Neuroscientist Who Lost Her Mind

barbara lipska

Photo courtesy of the Rubin Museum

On a recent night at New York’s Rubin Museum of Art, neuroscientist Barbara Lipska, Ph.D., sat down with journalist Jake Halpern as part of the museum’s annual Brainwave series. The discussion gave audience members the unique opportunity to hear a lucid perspective of what it’s like to experience psychosis. The interview was also particularly intimate because, in addition to his successful career as a writer, Halpern also happens to be Lipska’s son-in-law. His questions stemmed from firsthand experiences he shared with her as she battled malignant brain tumors that caused the psychotic episodes and nearly took her life.

As director of the Human Brain Collection Core at the National Institute of Mental Health, Lipska studies schizophrenia by analyzing postmortem brain dissections and observing the behavior of rats that have a disconnection between the hippocampus and prefrontal cortex. “They’re actually not as different as we would like to think,” she said of the rats. “They’re smaller, that’s for sure, and they don’t have this convoluted frontal cortex. But they are very intelligent animals, and they know what they have to do to get a reward.”

Continue reading

Changing the World with Smartphones

“We are wildly ambitious,” Tom Insel, M.D., says when asked about his plans for Verily Life Sciences, a research organization parented by Google. After 13 years, Insel rocked the world of brain science when he announced plans to step down as director of the National Institute of Mental Health (NIMH) in late 2015. His departure from NIMH, however, wasn’t a leave from neuroscience research or public health; it was a progressive step towards advancing the technologies that are predicted to transform mental health care.

Recently, Insel was profiled in the July/August 2017 issue of The Atlantic, which offers a thorough look at the trajectory that took him from lead role at the world’s largest mental health research institution to complete submersion in the energetic tech bubble of Silicon Valley.

The article recounts Insel’s early work in behavioral research, as well as his influence on the field of antidepressants and NIMH’s involvement in clinical drug trials. Presented with an opportunity to direct a new mental health team under Google, he could now focus on taking applied research and use it to help millions of people globally, who are in need of mental health care. “At any given moment, roughly one in seven of the world’s 7.5 billion people is struggling with mental illness. ‘We’re not going to reach all those people by hiring more psychiatrists,’ says Insel. But we might reach them with smartphones.”

Continue reading

Progress in BRAIN Initiative Research

brain_obama_robotics

President Barack Obama fist-bumps the robotic arm of Nathan Copeland during a tour at the White House Frontiers Conference at the University of Pittsburgh, Oct. 13, 2016. (Official White House Photo by Pete Souza)

In the less than three years since the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative was announced, researchers have made measurable progress towards creating new tools and sharpening existing ones to study the brain. Though its goals are long-term, in a few cases this progress already has shown promise in helping people.

These tools “allow us to do things that, in the past, were unimaginable,” said Nora Volkow of the National Institute of Drug Abuse during the third annual BRAIN Initiative investigators meeting, held in Bethesda, Md., this week. For example, imaging tech such as fMRI and PET have enabled us to make maps of brain activity and create a brain atlas of the concentration of serotonin transporters and receptors. But to reach goals as ambitious as characterizing the many types of neurons and other cells in the brain—or even to get a good count of how many types there are—we need to improve both the speed and the resolution of our tools.

Continue reading

Joshua Gordon Named New Head of NIMH

Guest Post by Kayt Sukel

joshua gordonIn late July, the National Institutes of Health (NIH) announced that it had finally completed its nearly year-long search for a new director of the National Institute of Mental Health (NIMH). Francis Collins, M.D., Ph.D., said that the agency had selected Joshua Gordon, M.D., Ph.D., currently an associate professor of psychiatry at Columbia University, to take the helm of the $1.5 billion federal agency governing mental health research, replacing former director Thomas Insel. He is expected to start in September.

 

In the press release announcing the selection, Collins said, “Josh is a visionary psychiatrist and neuroscientist with deep experience in mental health research and practice. He is exceptionally well qualified to lead the NIMH research agenda to improve mental health and treatments for mental illnesses. We’re thrilled to have him join the NIH leadership team.

Gordon, whose research program focused on integrative genetic models of psychiatric disease, spoke with the Dana Foundation about why he wanted to take on this new role in his career, the importance of collaboration and communication, and where he hopes to see the agency go under his leadership.

Continue reading

%d bloggers like this: