The time has finally come to announce this year’s champions of the Dana Foundation’s annual “Design a Brain Experiment” competition, where we asked high school students across the country to try their hand at creating an original science experiment to test theories about the brain. Every year, the competition judges face the challenge of selecting two winners from a tall stack of impressive submissions. However, this year made history with a first-ever tie for our second-place winners!
The first place prize of $500 goes to Medha Palnati from Westford Academy in Massachusetts for her impressive submission, “The Use of CRISPR Technology to Test Gene Therapy as a Treatment to Early-Onset Familial Alzheimer’s Disease in Zebrafish.” Palnati’s proposal explores the potential of using an exciting new experimental form of gene therapy to treat early-onset Familial Alzheimer’s disease (FAD). FAD is usually caused by an inherited gene mutation and occurs in about five percent of all people with Alzheimer’s disease. Palnati’s research proposal uses zebrafish as a model to test this potential therapy.