From the Archives: The Promise of Ketamine

promiseofketamine.jpgThis month, the FDA approved the use of esketamine, a nasal spray based on the old anesthetic and once-popular club drug ketamine, to treat people with severe depression that has not responded to other treatments. It’s costly and entails visiting the doctor for four hours a week for four weeks, but it’s the first treatment in decades that works in a new way in the brain. That means it might reach the large number of people with depression who are not helped by drugs that target other brain functions.

Last March, Ronald S. Duman, Ph.D., wrote for Cerebrum on “The Dazzling Promise of Ketamine,” exploring how the drug was validated as an antidepressant, how it works, and what it could mean for development of other drugs: Continue reading

Top 5 Dana Stories of 2018? From the Archives

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From the 2012 Cerebrum essay, “The Cognitive Benefits of Being Bilingual.” Photo: Getty Images

At www.dana.org, we have a deep archive of great stories about the brain and the people who study it, and thanks to the internet, none of it is further than a quick search away. When I checked the list of top stories from last year, I was pleased to see that you-all seem to like to read long stories—nearly all the top-read stories are in the longest format we post. But I was surprised that many of the stories are “classic” (i.e. way more than a few years old). This year we’ll be trying to figure out how to make our more-current stories on the same topics just as popular, but for now here are a few suggestions.

Here are the stories folks found most popular on www.dana.org last year.

1. Wounds That Time Won’t Heal: The Neurobiology of Child Abuse (Cerebrum, 2000)

Developmental neuropsychiatrist Martin H. Teicher describes how scientists are discovering startling connections between abuse of all kinds and both permanent debilitating changes in the brain and psychiatric problems ranging from panic attacks to post-traumatic stress. In these surprising physical consequences of psychological trauma, Teicher sees not only a wake-up call for our society but hope for new treatments. Continue reading

New Report Finds Current Strategies Insufficient for Preventing the Most Preventable Cause of Mental Illness

Guest blog by Brenda Patoine

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Image: Shutterstock

Childhood maltreatment is recognized as the No. 1 preventable cause of mental illness – and some experts argue, of all stress-related diseases – yet science still has no clear answers for how to best prevent the spiral of neglect and abuse that threatens millions of infants and children in the U.S. alone.

In a report published this week, the U.S. Preventive Services Task Force (USPTF), a U.S. Public Health Service committee charged with recommending action to thwart preventable health conditions, conceded that there was “insufficient data” to recommend any particular strategy that has been tested as a means of preventing childhood maltreatment, which encompasses neglect as well as physical, psychological, or sexual abuse. Preventive interventions initiated in primary care focus on preventing maltreatment before it occurs, as opposed to identifying children who are victims of abuse or neglect. Continue reading

2 Days Left to Vote for Your Favorite Sticker Design!

There are only two days left to vote for your favorite Brain Awareness Week 2019 sticker design! The winner will be featured on the 2019 Brain Awareness Week sticker used by partners across the US.

We have narrowed the choices to five wonderful designs and now it’s up to you! Cast your vote now through November 16.

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Our top five finalists are Leonor Braga, Joni Lahr-Moore, Luis Orazi, Brenda Ramos, Abby Salinero. Take a look at their designs and pick your favorite!

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The winners will be announced on November 26, so stay tuned!

– Amanda Bastone

Dana Press Offers Cerebrum Anthology 2017

anthology cover

When the cardboard cartons containing Cerebrum: Emerging Ideas in Brain Science 2018 arrived at our offices in midtown Manhattan a few weeks ago, pulling them out for the first time felt a bit like the birth of a new child. And like a newborn baby, each of the five anthology’s I’ve edited since coming to the Dana Foundation has its own look, personality, and distinct characteristics.

Let’s start with the look. The provocative cover is the work of J.F. Potevin, a French born, California-based artist whose work has appeared on the covers of Scientific American and Discover magazines. The cover also includes a complete list of contributors, many of them among the most distinguished neuroscientists in their research areas: Helen Mayberg on imaging, Beth Stevens on microglia, and Alvaro Pascual-Leone on deep brain stimulation, for example.

Continue reading

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